For women who want contraception only when they need it, Phexx® is convenient and easy to use1,2

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Phexx works immediately upon administration

After application, 1 dose of Phexx2:

  • will last up to 1 hour
  • provides protection for 1 act of vaginal intercourse

Instructions for your patients2:

Phexx gel icon
  • Intravaginally administer the contents of 1 pre-filled, single-dose applicator of Phexx before each episode of vaginal intercourse
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  • Administer an additional dose if intercourse does not occur within an hour of administration
  • An additional dose of Phexx needs to be used if vaginal intercourse occurs more than 1 time within 1 hour, the same way a new condom would be used for each episode of vaginal intercourse

Review the Instructions for Use and find helpful patient resources in the Resource Library.

Take a personalized approach to contraception with Phexx

What will patients get in a prescription for Phexx?

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EACH BOX contains 12 individual applicators packed in foil pouches
Graphic of Phexx applicator
EACH APPLICATOR contains one 5-gram dose of Phexx for single use

Patients using Phexx may refill 11 times per year

phexx carton 3-1

Not actual size.

Writing a prescription for Phexx

PHEXX VAGINAL GEL
(5-g APPLICATOR)

Sig: Administer 1 applicator intravaginally immediately before or up to 1 hour before EACH act of vaginal intercourse as needed.

Dispense: # 12 applicators (60 g total)

NDC: 69751-101-12

Refill: 11

phexx sample rx

Phexx vaginal gel is off-white to tan in color and is odorless and tasteless.

Phexxi applicator next to Phexxi gel

Not actual size.

Starting on Phexx is simple Starting on Phexx is simple

Starting on Phexx is simple

  • No switch protocol is required
  • Phexx is used only when needed—without prior onboarding or monitoring

Phexx has no contraindications2

  • However, Phexx should be avoided in women who have had recurrent urinary tract infections or abnormalities, or are using a vaginal ring. Phexx should also be avoided if the woman or her partner is allergic to any of the ingredients in Phexx.

Concomitant use2

  • Phexx may be used with latex, polyurethane, and polyisoprene condoms; and vaginal diaphragms. Avoid Phexx use with vaginal rings.
How does Phexx work?

How does Phexx work?

 

The unique MOA of Phexx maintains an acidic vaginal pH to reduce sperm motility.

Proven contraceptive protection.

Proven contraceptive protection.

 

Results from the clinical trial show Phexx is effective and safe.

Learn more about Phexx.

Learn more about Phexx.

 

Get in touch with an Evofem Representative for more information about Phexx.

INDICATION

Phexx is indicated for the prevention of pregnancy in females of reproductive potential for use as an on-demand method of contraception.

LIMITATIONS OF USE

Phexx is not effective for the prevention of pregnancy when administered after intercourse.

IMPORTANT SAFETY INFORMATION

WARNINGS AND PRECAUTIONS

Few cases (0.36%) of adverse reactions of cystitis, pyelonephritis and other upper urinary tract infection (UTI) have been reported in Phexx clinical studies. Of these, one case of pyelonephritis was considered serious and required hospitalization. Avoid use of Phexx in females with history of recurrent urinary tract infection or urinary tract abnormalities.

ADVERSE REACTIONS

Most common adverse reactions were vulvovaginal burning sensation, pruritus, mycotic infection, genital discomfort (including male partners); urinary tract infection, bacterial vaginosis, vaginal discharge, and dysuria. Patients should consult their healthcare provider for severe or prolonged genital irritation or urinary tract symptoms.

Advise the patient:

  • To discontinue Phexx if they develop a local hypersensitivity reaction.
  • That Phexx does not protect against HIV infection or other sexually transmitted infections.
  • Avoid Phexx use with vaginal rings.

To report SUSPECTED ADVERSE REACTIONS, contact Evofem at toll-free phone 1-833-EVFMBIO or you may contact FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please see full Prescribing Information for Phexx.

References:

  1. Data on file. Evofem Biosciences, Inc.
  2. Phexx® [Prescribing Information]. Evofem Biosciences, Inc.: San Diego, CA; April 2025.

IMPORTANT SAFETY INFORMATION

WARNINGS AND PRECAUTIONS

Few cases (0.36%) of adverse reactions of cystitis, pyelonephritis and other upper urinary tract infection (UTI) have been reported in Phexx clinical studies. Of these, one case of pyelonephritis was considered serious and required hospitalization. Avoid use of Phexx in females with history of recurrent urinary tract infection or urinary tract abnormalities.

ADVERSE REACTIONS

Most common adverse reactions were vulvovaginal burning sensation, pruritus, mycotic infection, genital discomfort (including male partners); urinary tract infection, bacterial vaginosis, vaginal discharge, and dysuria. Patients should consult their healthcare provider for severe or prolonged genital irritation or urinary tract symptoms.

Advise the patient:

  • To discontinue Phexx if they develop a local hypersensitivity reaction.
  • That Phexx does not protect against HIV infection or other sexually transmitted infections.
  • Avoid Phexx use with vaginal rings.

To report SUSPECTED ADVERSE REACTIONS, contact Evofem at toll-free phone 1-833-EVFMBIO or you may contact FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please see full Prescribing Information for Phexx.

INDICATION

Phexx is indicated for the prevention of pregnancy in females of reproductive potential for use as an on-demand method of contraception.

LIMITATIONS OF USE

Phexx is not effective for the prevention of pregnancy when administered after intercourse.